Zammit and colleagues (2002) reported a 27-year follow-up of the Swedish cohort study. This study improved on the earlier study in the following ways: the psychiatric register provided more complete coverage of cases diagnosed with schizophrenia; and there was better statistical control of more potentially confounding variables, including other drug use, IQ, known risk factors for schizophrenia and social integration. Cannabis use at baseline predicted a dose–response relationship between the frequency of cannabis use at age 18 and the risk of schizophrenia during the follow-up. The relationship persisted after statistically controlling for the effects of other drug use and other potential confounding factors, including a history of psychiatric symptoms at baseline. They estimated that 13 percent of cases of schizophrenia could be averted if all cannabis use were prevented.
Some manufacturers ship CBD products nationally, an illegal action which the FDA has not enforced in 2018, with CBD remaining the subject of an FDA investigational new drug evaluation, and is not considered legal as a dietary supplement or food ingredient as of December 2018.[70][71] Federal illegality has made it difficult historically to conduct research on CBD.[72] CBD is openly sold in head shops and health food stores in some states where such sales have not been explicitly legalized.[73][74]
In support of the previous study by Power et al. (in press), a second study by Giordano, Ohlsoon, Sundquist, Sundquist, and Kendler (2015) found that the relationship between cannabis use or abuse and schizophrenia may not be as strong as believed. The authors found that as the degree of shared genetic and environmental factors increased (beginning with first cousins to full siblings), the relationship between schizophrenia and cannabis abuse decreased, although it remained significant even in full sibling pairs.
In the UK, the Department for Environment, Food and Rural Affairs treats hemp as a purely non-food crop, but with proper licensing and proof of less than 0.2% THC concentration, hemp seeds can be imported for sowing or for sale as a food or food ingredient.[19] In the U.S., imported hemp can be used legally in food products and, as of 2000, was typically sold in health food stores or through mail order.[16]
There has actually been a substantial amount of experiments done on cannabidiol that has proved its potential healing powers. Dr. Sean McAllister, a scientist from the Pacific Medical Center in San Francisco, made an astounding discovery about CBD. McAllister has been studying cannabinoid compounds for 10 years now in search of new therapeutic interventions for various cancers. He discovered that cannabidiol is a potent inhibitor of cancer cell proliferation, metastasis, and tumor growth.
The leaves have a peculiar and diagnostic venation pattern that enables persons poorly familiar with the plant to distinguish a cannabis leaf from unrelated species that have confusingly similar leaves (see illustration). As is common in serrated leaves, each serration has a central vein extending to its tip. However, the serration vein originates from lower down the central vein of the leaflet, typically opposite to the position of, not the first notch down, but the next notch. This means that on its way from the midrib of the leaflet to the point of the serration, the vein serving the tip of the serration passes close by the intervening notch. Sometimes the vein will actually pass tangent to the notch, but often it will pass by at a small distance, and when that happens a spur vein (occasionally a pair of such spur veins) branches off and joins the leaf margin at the deepest point of the notch. This venation pattern varies slightly among varieties, but in general it enables one to tell Cannabis leaves from superficially similar leaves without difficulty and without special equipment. Tiny samples of Cannabis plants also can be identified with precision by microscopic examination of leaf cells and similar features, but that requires special expertise and equipment.[12]
There are thousands of unique varieties of hemp. The cultivars used for CBD oil contain significantly higher concentrations of CBD than others. Using these uniquely potent plants, it is possible to extract cannabis oil that contains significant levels of cannabidiol, as well as essential vitamins, minerals, fatty acids, terpenes, flavonoids, and other non-psychoactive cannabinoids.

Cannabis consumers have long prized potency (a high THC content) as one of the main factors that makes a particular strain more desirable. Though traditional demand for THC has caused an oversaturation of high-potency products, many consumers are starting to prefer less intense products that are lower in THC and higher in the non-intoxicating compound called cannabidiol (CBD).

There is great variation in Cannabis sativa, because of disruptive domestication for fiber, oilseed, and narcotic resin, and there are features that tend to distinguish these three cultigens (cultivated phases) from each other. Moreover, density of cultivation is used to accentuate certain architectural features. Figure 5 illustrates the divergent appearances of the basic agronomic categories of Cannabis in typical field configurations.
In 2015, The Hebrew University of Israel published a study that documented the potency of single-molecule CBD extract versus the potency of whole-plant CBD-rich extract. It found that extract taken from whole plant CBD-rich cannabis is therapeutically superior to single-molecule extract. The scientists behind this study noticed that science had been utilizing pure, single-molecule CBD, which resulted in a bell-shaped dose-response curve. This means that CBD’s efficacy plummets at very high and very low doses.
It’s easy to see why vaping has become such a popular method for consuming marijuana. The method is remarkably discrete and produces none of the telltale “weed smells” that often betray cannabis users. Vape pens and other hand-held devices are portable and convenient. They’re free of many of the harsh marijuana plant compounds that can harm your lung health, like tars. And companies are getting better at crafting high-quality, flavorful vape cartridges with a wide array of cannabinoid profiles.
About half of the world market for hemp oil is currently used for food and food supplements (de Guzman 2001). For edible purposes, hempseed oil is extracted by cold pressing. Quality is improved by using only the first pressing, and minimizing the number of green seeds present. The oil varies in color from off-yellow to dark green. The taste is pleasantly nutty, sometimes with a touch of bitterness. Hemp oil is high in unsaturated fatty acids (of the order of 75%), which can easily oxidize, so it is unsuitable for frying or baking. The high degree of unsaturation is responsible for the extreme sensitivity to oxidative rancidity. The oil has a relatively short shelf life. It should be extracted under nitrogen (to prevent oxidation), protected from light by being kept in dark bottles, and from heat by refrigeration. Addition of anti-oxidants prolongs the longevity of the oil. Steam sterilization of the seeds, often required by law, allows air to penetrate and so stimulates rancidity. Accordingly, sterilized or roasted hemp seeds, and products made from hemp seed that have been subjected to cooking, should be fresh. The value of hemp oil from the point of view of the primary components is discussed below. In addition, it has been suggested that other components, including trace amounts of terpenes and cannabinoids, could have health benefits (Leizer et al. 2000). According to an ancient legend (Abel 1980), Buddha, the founder of Buddhism, survived a 6-year interval of asceticism by eating nothing but one hemp seed daily. This apocryphal story holds a germ of truth—hemp seed is astonishingly nutritional.
CBC is another lesser-known yet still crucial cannabinoid in marijuana, especially from a therapeutic perspective. While bereft of the psychoactive quality of THC (and to a lesser extent THCV), CBC is gaining popularity as an anxiety reducer. While research on cannabichromene lags behind others, there’s good reason to continue looking into its potential as a medicine.

Aqua, Sodium Acrylates Copolymer Lecithin, Glycerin, Allantoin, Sodium Hyaluronate, Stearic Acid, Cetyl Alcohol, Stearyl Alcohol, Glycol Distearate, Menthol, Glyceryl Stearate, PEG-100 Stearate, Tocopheryl Acetate, Emu Oil, Cocos Nucifera (Coconut Oil), Squalene, Cannabis Sativa Seed Oil (Hemp Seed Oil)< Arnica Montana Flower Extract, Boswellia Serrata Resin Extract, Aloe Barbadensis Leaf Juice, Phenoxyethanol, Ethylhexylglycerin, Gluconolactone, Sodium Benzoate, Calcium Gluconate
Selection for fiber has resulted in strains that have much more bark fiber tissues and much less woody core than encountered in narcotic strains, oilseed strains, and wild plants (Fig. 12). In non-fiber strains of Cannabis, bark can be less than one quarter of the stem tissues (i.e. more than three quarters can be woody core). By contrast, in fiber strains half of the stem tissues can be bark, and more than half of this can be the desirable long primary fibers (de Meijer 1995). Non-fiber strains rarely have as much as 15% fiber in the bark.
^ Vanyukov MM, Tarter RE, Kirillova GP, Kirisci L, Reynolds MD, Kreek MJ, Conway KP, Maher BS, Iacono WG, Bierut L, Neale MC, Clark DB, Ridenour TA (June 2012). "Common liability to addiction and "gateway hypothesis": theoretical, empirical and evolutionary perspective". Drug and Alcohol Dependence (Review). 123 Suppl 1: S3–17. doi:10.1016/j.drugalcdep.2011.12.018. PMC 3600369. PMID 22261179.
Since then, many different types of sex determination systems have been discovered, particularly in plants.[15] Dioecy is relatively uncommon in the plant kingdom, and a very low percentage of dioecious plant species have been determined to use the XY system. In most cases where the XY system is found it is believed to have evolved recently and independently.[31]

The heat is very much on CBD oil sellers these days as the FDA continues to crack down on companies selling “questionable” (to put it nicely) hemp-based products. In fact, since 2015 – when the FDA first issued warning letters to multiple CBD sellers – the industry has been forced to clean up its act, at least in terms of manufacturing operations and brand transparency.
The scientific debate regarding taxonomy has had little effect on the terminology in widespread use among cultivators and users of drug-type Cannabis. Cannabis aficionados recognize three distinct types based on such factors as morphology, native range, aroma, and subjective psychoactive characteristics. Sativa is the most widespread variety, which is usually tall, laxly branched, and found in warm lowland regions. Indica designates shorter, bushier plants adapted to cooler climates and highland environments. Ruderalis is the informal name for the short plants that grow wild in Europe and Central Asia.
But he wasn’t finished. In February of 1980, Dr. Mechoulam teamed up with South American researchers to publish a study regarding cannabis and epilepsy. This study is seen as one of the earliest double-blind studies of CBD on clinical subjects. The study Dr. Mechoulam and his team conducted included 16 people, many of whom were children, who all suffered from severe epilepsy. The results were startling: Every subject who received CBD experienced improvement in their condition with little to no side effects. This anticonvulsant study has since proven to be an integral milestone in the world of clinical marijuana research, but largely went unnoticed at the time.
While Jenna’s “How I cured my celiac disease” story is inspiring and research into the therapeutic effects of CBD is promising, especially in the treatment of seizures and other neurological disorders, the FDA is clear: Marketing supplements as having the ability to treat, cure, alleviate the symptoms of, or prevent developing diseases is simply not permitted by law. Yet that has not stopped Jenna and distributors from claiming that HempWorx treats a number of diseases, including Parkinson’s, multiple sclerosis, AIDS and cancer, often as an alternative to traditional treatments. In fact, has amassed a database of more than 100 inappropriate and illegal health claims. They include:
If you really want something that’s ultra-low dose, these goji berries are the way to go. At 1mg THC and 2mg CBD per piece, there’s no going wrong. And it’s even more delicious than Plus Products’ pineapple and coconut gummies. Beware though: They’re beyond tasty so it’s very easy to forget that they actually contain cannabis. The organic goji berries are sourced from Tibet via Imlak’esh Organics and the chocolate complements them perfectly. I could eat three handfuls. But, of course, I won’t.
Several animal studies have led researchers to believe that cannabis could reverse signs of aging in the brain. Aging mice treated with small daily doses of THC showed a reversal in cognitive decline. However, past studies on the effects of cannabis on human memory show less promising results. Still, with few viable treatments for dementia, medical marijuana is receiving increased attention in this area.
CBD has some other very important jobs outside of the endocannabinoid system (ECS). For instance, CBD mildly activates one of the brain’s predominant serotonin receptors (5-HT1A), which may explain CBD’s effects on depression and anxiety. It also acts at the peroxisome proliferator activated receptors (PPARs), which halt the proliferation of cancer cells and convey neuro- and cardioprotection. By interacting with a particular PPAR (gamma), CBD could prove to be a promising new way to prevent alzheimer’s disease and other brain disorders.
Cannabis sativa is an annual wind-pollinated plant, normally dioecious and dimorphic, although sometimes monoecious (mostly in several modern European fiber cultivars). Figure 2 presents the basic morphology of the species. Some special hybrids, obtained by pollinating females of dioecious lines with pollen from monoecious plants, are predominantly female (so-called “all-female,” these generally also produce some hermaphrodites and occasional males). All-female lines are productive for some purposes (e.g. they are very uniform, and with very few males to take up space they can produce considerable grain), but the hybrid seed is expensive to produce. Staminate or “male” plants tend to be 10%–15% taller and are less robust than the pistillate or “female” (note the comparatively frail male in Fig. 3). So prolific is pollen production that an isolation distance of about 5 km is usually recommended for generating pure-bred foundation seed. A “perigonal bract” subtends each female flower, and grows to envelop the fruit. While small, secretory, resin-producing glands occur on the epidermis of most of the above-ground parts of the plant, the glands are very dense and productive on the perigonal bracts, which are accordingly of central interest in marijuana varieties. The root is a laterally branched taproot, generally 30–60 cm deep, up to 2.5 m in loose soils, very near the surface and more branched in wet soils. Extensive root systems are key to the ability of hemp crops to exploit deep supplies of nutrients and water. The stems are erect, furrowed, and usually branched, with a woody interior, and may be hollow in the internodes. Although the stem is often woody, the species is frequently referred to as a herb or forb. Plants vary enormously in height depending on genetic constitution and environment (Fig. 4), but are typically 1–5 m (heights of 12 m or more in cultivation have been claimed).
Another thing I learned: CBD becomes more effective when taken in conjunction with a low dose of THC (tetradhydrocannabinoid, the psychoactive component of cannabis). For those who worry about getting high, fear not. I was initially concerned about the possibility of diminished faculties. After all, many single-serving THC edibles start at 10mg—but it’s good to note that most people won’t need even half as much. So you can do as I do and cut THC chocolate squares or gummies as you see fit—and then “pair” them with a CBD edible or tincture. I’ve also started to microdose edibles that contain both CBD and THC. (I quarter or halve a Dixie Synergy Milk Chocolate 1:1 depending on how I feel.)
Hemp has at times in the past been grown simply for its ornamental value. The short, strongly-branched cultivar ‘Panorama’ (Fig. 43) bred by Iván Bósca, the dean of the world’s living hemp breeders, was commercialized in Hungary in the 1980s, and has been said to be the only ornamental hemp cultivar available. It has had limited success, of course, because there are very few circumstances that permit private gardeners can grow Cannabis as an ornamental today. By contrast, beautiful ornamental cultivars of opium poppy are widely cultivated in home gardens across North America, despite their absolute illegality and the potentially draconian penalties that could be imposed. Doubtless in the unlikely event that it became possible, many would grow hemp as an ornamental.
Despite advanced analytical techniques, much of the cannabis used recreationally is inaccurately classified. One laboratory at the University of British Columbia found that Jamaican Lamb's Bread, claimed to be 100% sativa, was in fact almost 100% indica (the opposite strain).[83] Legalization of cannabis in Canada (as of October 17, 2018) may help spur private-sector research, especially in terms of diversification of strains. It should also improve classification accuracy for cannabis used recreationally. Legalization coupled with Canadian government (Health Canada) oversight of production and labelling will likely result in more—and more accurate—testing to determine exact strains and content. Furthermore, the rise of craft cannabis growers in Canada should ensure quality, experimentation/research, and diversification of strains among private-sector producers.[84]
Hi, I'm Shane and welcome to Here you will find honest and accurate information about CBDs, medical marijuana, hemp, and much more. I am passionate about using CBDs to enhance and improve life, and it is my goal to share the most up-to-date information and research with our readers. Visit our about page to learn more about me and the HempCaptain mission. Thanks for visiting!
For home cooks like me, I recommend CBD extra virgin olive oil because of its versatility. You can drizzle it on everything from salads to pizza and even brambleberry ice cream. I even make a miso-honey glaze while using a little bit of the stuff. In particular, I’m a big fan of Pot d’Huile, which was founded by San Francisco-based Yannick Crespo. It’s stellar. For one thing, it tastes exactly the way good EVOO should—with none of that “green” marijuana aftertaste. It also doesn’t remind me of Bertolli—not that there’s anything wrong with it. But you know, delicious EVOO is nothing like Bertolli. Crespo attributes Pot d’Huile’s non-compromising flavor with the ethanol extraction process that the company uses, which is slightly more expensive—in addition to using locally-sourced oil from Northern California. The flavor is so good that Pot d'Huile regularly hosts pop-up dinners with chefs who are so into it. (And if you ever find yourself in a city where they’re hosting, it’d be a shame to skip out.) But beyond all that, Pot d’Huile makes dosing easy: It’s 1mg of CBD per 1ml of olive oil. So all you’ll really need to incorporate CBD EVOO into your meals are measuring spoons. And yes, they do have THC olive oils as well—at $50 for 100ml. In the future, the company also has plans on creating a THC–CBD oil. Easy peasy.
Hexo Corp. shares HEXO, +6.63% HEXO, +5.81%  rose 3.9% after the Quebec-based company said it has agreed to acquire its smaller rival, Toronto-based Newstrike Brands Ltd. NWKRF, +10.95% HIP, +11.11%  in an all-stock deal valued at about C$263 million. Newstrike shareholders will receive 0.06332 Hexo shares for each Newstrike share owned. Both boards have approved the deal which must now be approved by shareholders.
Mental illness is described as 'the spectrum of cognitive, emotional, and behavioral conditions that interfere with social and emotional well-being and the lives and productivity of people. Having a mental illness can seriously impair, temporarily or permanently, the mental functioning of a person. Other terms include: 'mental health problem', 'illness', 'disorder', 'dysfunction'.[37]
HempWorx earns bonus points right out of the gate by choosing to use domestically grown, organic, and non-GMO hemp, and knocks it out of the park with their evident passion for educating the public on the uses, history, and science of cannabinoids. Fun facts (such as the fact that the first American flag was made out of hemp) add a rich critical thinking element to the customer’s experience. Instead of touting it as just another supplement, HempWorx gives homage to the long-standing legacy, magic, and controversy of the heralded cannabis plant.
This is the worst company I have dealt with they take weeks to ship I set up for auto ship and on my third month after 10 days it's still had not been shipped after I contacted them they said they did not have my unit number in the address they sent me it was right there so when I asked him to send a complimentary bottle to make up for the weeks I've had to wait in between orders they said they don't do that I said cancel my auto-ship and refund my credit card they don't do that they said I have to wait till I receive the product and send it back and apply for a refund I could not recommend this company to anyone although I think the product is good but it does defeat the purpose if you're waiting weeks in between running out
HempWorx earns bonus points right out of the gate by choosing to use domestically grown, organic, and non-GMO hemp, and knocks it out of the park with their evident passion for educating the public on the uses, history, and science of cannabinoids. Fun facts (such as the fact that the first American flag was made out of hemp) add a rich critical thinking element to the customer’s experience. Instead of touting it as just another supplement, HempWorx gives homage to the long-standing legacy, magic, and controversy of the heralded cannabis plant.
We have been using cannabis oil with a 1:1 CBD/THC ratio from “AnnCannMed” in treating my husband with pancreatic cancer with a lot of improvement since 4 weeks and the product is working in a miraculous way beyond our expectations. The medication is working with super proof. We recommend you visit AnnCannMed for your health prescriptions and medical purchases and feel support talking to licensed physicians